Science Weekly: neuroscience, climate science, nutrition

Review questions whether carb-loading helps once placebo and in-race fuelling are controlled

A thin week: I could verify few papers inside the window, so this edition adds dated items from the prior 30 days, all read through your half-marathon lens (nutrition and heat physiology). I found no verified neuroscience or climate-science paper this week.

The 30-second version
  1. A Sept 2026 review in IJSNEM finds carb-loading evidence weak once blinding and in-race carbohydrate are considered.
  2. A Eur J Sport Sci study (10 men) finds perceived strain tracks heat strain but can't replace measurement.
  3. Blueberry 'faster half marathon' headlines rest on a nine-runner, industry-funded trail trial in IJSNEM.
01IJSNEM · Sept issue

Carb-loading's benefit is unproven once placebo and in-race fuelling are controlled

Design: a critical review of 14 published carbohydrate-loading studies (not a new trial). Only two were double-blind, placebo-controlled; only four gave carbohydrate during exercise. Both double-blind studies, which also gave in-exercise carbohydrate, found no performance benefit.

The other two in-exercise-carbohydrate studies showed a benefit of moderate size, Cohen's d about 0.35, which the authors say is comparable to effects reported for placebo nutrition interventions. Limits: few studies, mixed test types (time-to-exhaustion vs time trial), and it concerns ~90-240 minute efforts. I worked from the abstract; funding and conflict statements were not available to me. Consult a qualified professional before changing diet or training.

Bottom line: weak, mostly indirect evidence; it doesn't show carb-loading fails, only that its benefit is unproven when fuelling during exercise and blinding are handled properly.

02Eur J Sport Sci · Sep 9

In heat, how hard it feels tracks body strain, but isn't interchangeable

Design: randomized crossover trial in 10 healthy, active, non-heat-acclimated men (mean age 29), cycling 60 minutes in hot-dry and warm-humid conditions with equal wet-bulb globe temperature. A perceptual strain index (from effort and thermal sensation) correlated very strongly with physiological strain indices (r = 0.94-0.98).

But agreement was loose: limits of agreement ran from -2.8 to 4.2 arbitrary units, so the authors say the measures are not interchangeable. Limits: ten men, cycling not running, indoor lab. Date caveat: the Exa index lists Sep 9; the Wiley listing shows Oct 1, so the exact online date is unconfirmed. Funding not found. Heat illness is serious; consult a qualified professional about hot-weather training.

Bottom line: small lab study, modest evidence; feeling-based strain is a rough screen for heat stress, not a safety measurement.

03Claim checked: Runner's World · Sep 24

Claim checked: 'blueberries improve half-marathon time' overreaches a nine-runner trial

Runner's World coverage (Sep 24) of an IJSNEM study, plus a UFV release (Sep 14). The study was a double-blind, placebo-controlled crossover in nine recreational trail runners: seven days of freeze-dried blueberry powder vs placebo before a simulated 22.2 km trail race. Race time was faster with blueberries (p = .003); the university says about seven and a half minutes, and Runner's World reports 2:37:05 vs 2:44:30 (4.2%). Heart rate and perceived exertion did not differ.

Limits: n = 9, one trail course, no road or half-marathon test; the dose was about three cups of berries daily by the researchers' calculation. The US Highbush Blueberry Council funded it. Earlier lab studies by the same authors found no differences. I could not open the journal page; I used the abstract and press accounts.

Claim checked: partly supported for trail racing in nine runners; not shown for half marathons, and industry funding warrants caution.

Watch next week for new IJSNEM and Journal of Applied Physiology issue releases on fuelling, and fresh climate and neuroscience papers I could not verify this week.

Coverage: Sep 28 – Oct 5, 2026 (plus verified items back to Sep 5)

Researched with GREP. Every story links to its sources.

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